The South Florida Bulls open American Conference play when they take on the Charlotte 49ers on Friday night. Charlotte is coming off a 28-17 loss to Rice on Sept. 18, while South Florida cruised to a 63-14 win over South Carolina State on Sept. 20. The 49ers (1-3, 0-1 American), who were 5-7 overall in 2024, will be playing their first true road game of the year. The Bulls (3-1, 0-0 American), who are 1-0 against unranked opponents, are 2-0 on their home field.
Kickoff from Raymond James Stadium in Tampa, Fla., is at 7 p.m. ET. South Florida leads the all-time series 2-0, including a 59-24 win last season at Charlotte. The Bulls are 28-point favorites in the latest Charlotte vs. South Florida odds, while the over/under for total points scored is 55.5 via SportsLine consensus.
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The model has simulated Charlotte vs. South Florida 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in well over 60% of simulations!
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Written by Daniel Kohn
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