The No. 3 Clemson TIgers seek their second straight national championship and third in four years when they collide with the top-ranked LSU TIgers in the 2020 College Football Playoff National Championship Game on Monday. Kickoff from the Mercedes-Benz Superdome is set for 8 p.m. ET.

LSU is a 5.5-point favorite, while the over-under for total points scored is 67. Before making any LSU vs. Clemson picks or CFP National Championship Game predictions, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of almost $4,000 for $100 players on its top-rated college football picks against the spread. It also went a sizzling 8-2 on all picks against the spread during Championship Week. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on LSU vs. Clemson in the CFP National Championship Game. We can tell you it's leaning Under, and it's also generated a STRONG against-the-spread pick that cashes in nearly 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

So who wins LSU vs. Clemson in the CFP National Championship Game? And which side of the spread can you bank on in almost 60 percent of simulations? ... Join SportsLine right now to find out which side of the LSU vs. Clemson spread to back, all from the advanced model that has generated a stunning profit of almost $4,000 for $100 players on its top-rated picks!