The St. Louis Cardinals will look to even their three-game series at 1-1 when they battle the Detroit Tigers in an interleague matchup on Saturday. The Tigers posted a 4-0 win over St. Louis in Detroit's home opener on Friday. The Cardinals (4-3), who had a two-game winning streak snapped, were fourth in the National League Central at 78-84 a year ago. The Tigers (3-4), who stopped a four-game losing streak, were second in the American League Central at 87-75 in 2025.
First pitch from Comerica Park in Detroit is set for 1:10 p.m. ET. The Tigers lead the all-time series 41-28, including wins in five of the last six meetings. Detroit is a -163 favorite on the money line (risk $163 to win $100) in the latest Cardinals vs. Tigers odds, while the over/under is 7.5.
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Written by Daniel Kohn
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