Cardinals vs. Reds odds, line, prediction: 2026 MLB picks for Thursday, Aug. 20, from proven model
SportsLine's projection model, which entered Week 22 of the MLB season on a 49-31 run, has locked in its MLB predictions for the St. Louis Cardinals vs. Cincinnati Reds on Thursday afternoon

A rare five-game series concludes on the Thursday MLB schedule as the St. Louis Cardinals visit the Cincinnati Reds. After splitting a Monday doubleheader, St. Louis (65-63) took Tuesday's contest before Cincy (61-66) took Wednesday's game, setting up the rubber match. Michael McGreevy (5-9, 3.48 ERA) will get the ball for the Cardinals, while the Reds trot out Brady Singer (5-11, 4.66 ERA).
