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Cardinals vs. Padres odds, lines: Proven model reveals MLB picks for May 16, 2021, Sunday Night Baseball game

SportsLine's Projection Model generated a pick for Sunday night's National League matchup between St. Louis and San Diego
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The San Diego Padres go for a three-game sweep of the St. Louis Cardinals when they meet in MLB action on Sunday night. First pitch is at 7:08 p.m. ET at Petco Park in San Diego. William Hill Sportsbook lists San Diego as the -125 favorite (risk $125 to win $100) in the latest Cardinals vs. Padres odds. The Over-Under for total runs is set at seven (see the latest lines for every game on our MLB odds page) in this matchup.

Before making any Cardinals vs. Padres picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It is off to a fast start in 2021, going 44-31 on top-rated MLB money-line picks through six weeks, returning over $700. Anyone following it has seen HUGE rewards! 

Now, it has set its sights on Cardinals vs. Padres. We can tell you it's leaning Over, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Cardinals vs. Padres? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the Cardinals vs. Padres money line you should be all over on Sunday, all from the model that was up over $1,400 on MLB picks in 2019!

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SportsLine Staff
SportsLine Staff