Cardinals vs. Cubs odds, line, prediction: 2026 MLB picks for Friday, Aug. 14, from proven model
SportsLine's projection model, which entered Week 21 of the MLB season on a 45-30 run, has locked in its MLB predictions for the St. Louis Cardinals vs. Chicago Cubs on Friday afternoon
The Chicago Cubs look to get back on track when they battle the rival St. Louis Cardinals in a key National League Central matchup on Friday afternoon. Chicago dropped a 7-0 decision at Washington on Thursday, while St. Louis downed Philadelphia 7-1 on Wednesday. The Cardinals (61-60), who are third in the division, are 29-26 on the road this season. The Cubs (71-51), who are second in the NL Central, are 35-24 on their home field in 2026.
