Cardinals vs. Blue Jays odds, line, prediction: 2026 MLB picks for Saturday, Aug. 1 from proven model

An interleague matchups gets the Saturday MLB schedule underway as the St. Louis Cardinals and Toronto Blue Jays match up. The Cardinals are 54-56 and three games back from the final wild-card spot in the NL. The Blue Jays are 51-59 and 4.5 games out of the AL wild-card picture. St. Louis lefty rookie Quinn Matthews will make his MLB debut, while righty Kevin Gausman (4-10, 4.51 ERA) is on the hill for Toronto.

First pitch from Rogers Centre in Toronto is set for 3:07 p.m. ET. Toronto is a -144 favorite on the money line (risk $144 to win $100) in the latest Blue Jays vs. Cardinals odds, while the over/under, is 8.5. Before making any Cardinals vs. Blue Jays picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 19 of the MLB season on a sizzling 39-23 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has simulated Blue Jays vs. Cardinals 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

Who wins Cardinals vs. Blue Jays, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model that entered Week 19 of the MLB season on a red-hot 39-23 run!