An AFC West rivalry will be renewed in NFL Week 10 on 'Thursday Night Football' as the Denver Broncos host the Las Vegas Raiders. Denver (7-2) is tied for the best record in the league, is riding an NFL-high six-game win streak and is coming off an 18-15 road win at Houston. Meanwhile, Las Vegas (2-6) lost in overtime to Jacksonville on Sunday, 30-29, and has the fourth-worst point differential (-78) in the NFL. The Broncos swept the season series a year ago. Reigning Defensive Player of the Year Patrick Surtain II (pec) is out for Denver.

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Kickoff is at 8:15 p.m. ET from Empower Field at Mile High in Denver. The Broncos swept the season series in 2024, after the Raiders had won each of the previous eight meetings. The Raiders are 7-3 ATS over the last 10 matchups. The latest Broncos vs. Raiders odds have Denver as the 9.5-point favorites. The over/under for total points scored is 43. Denver is at -521 on the money line (risk $521 to win $100), with Vegas at +388 (risk $100 to win $388).

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