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After missing the postseason for the first time in over a decade, the Kansas City Chiefs look to return to form when they kick off their 2025 season against the defending AFC West champion Denver Broncos on Monday Night Football. The game will mark the return of Chiefs quarterback Patrick Mahomes, who missed a chunk of last season with a torn ACL and MCL, suffered in December. The Chiefs, who finished third in the AFC West, were 6-11 overall in 2025. The Broncos, who tied for the best record in the NFL a year ago, were 14-3. Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here:
Kickoff is at 8:15 p.m. ET from GEHA Field at Arrowhead Stadium in Kansas City, Mo. The latest Broncos vs. Chiefs odds have Kansas City as a 2.5-point favorite, while the over/under for total points scored is 43.5.
Before making any Broncos vs. Chiefs picks, or Monday Night Football predictions of your own, you NEED to see what SportsLine expert Brady Kannon has to say.
Vegas-based Brady Kannon joined SportsLine for the 2025 NFL season and delivered immediate results, finishing 41-31-2 (+7.95 units). That included a 3-0 Super Bowl in which he called A.J. Barner scoring a touchdown (+240) and Drake Maye throwing an interception. He enters this season on a 32-15-2 roll on NFL picks, returning $1,648 to $100 players! Anyone following his picks could have seen huge returns.
Now, Kannon has locked in another confident pick for Broncos vs. Chiefs.
He's leaning Under the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.
So who wins Broncos vs. Chiefs on Monday night, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine RIGHT NOW to see which side of the Broncos vs. Chiefs line to back, all from the expert who has returned $1,648 to $100 players in his last 49 NFL picks!
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Written by Daniel Kohn
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