The Milwaukee Brewers face the Boston Red Sox in the third and deciding game of their interleague series on Wednesday afternoon. Boston is coming off a 3-2 win on Tuesday night. The Brewers (8-3), who lead the National League Central Division, have won three of their five road games this season. The Red Sox (3-8), who are fifth in the American League East, are 2-3 on their home field in 2026.
First pitch from Fenway Park in Boston is set for 1:35 p.m. ET. The Red Sox lead the all-time series 224-199, but the Brewers have won six of the past eight meetings. Boston is a -139 favorite on the money line (risk $139 to win $100) in the latest Brewers vs. Red Sox odds, while the over/under, is 7.5. Before making any Brewers vs. Red Sox picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.