A series win will be on the line when the Toronto Blue Jays battle the Pittsburgh Pirates in an interleague matchup on Wednesday afternoon. The Blue Jays (74-53), who lead the American League East division, are 32-32 on the road this season. The Pirates (53-74), who are fifth in the National League Central, are 35-30 on their home field in 2025.
First pitch from PNC Park in Pittsburgh is set for 12:35 p.m. ET. The Blue Jays have won eight of the past 10 meetings with the Pirates. Toronto is a -152 favorite on the money line (risk $152 to win $100) in the latest Blue Jays vs. Pirates odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over-under, is 8 in the latest MLB odds.
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Written by Daniel Kohn
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