Two AFC hopefuls will kick off NFL Week 12 as the Buffalo Bills visit the Houston Texans on 'Thursday Night Football.' Buffalo (7-3) sits in second place of the AFC East and has won three of its last four, with it coming off a 44-32 win over Tampa on Sunday. Houston (5-5) is third in the AFC South, has also won three of four and most recently notched a 16-13 win over Tennessee in Week 11. Houston won the last matchup as it defeated Buffalo, 23-20, at home in 2024. Houston quarterback C.J. Stroud (concussion) has been ruled out, as has Bills tight end Dalton Kincaid (hamstring), while receiver Keon Coleman is inactive for the second straight week. The Bills are currently the No. 5 seed in the AFC, while Houston is the No. 8 seed.
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Kickoff is at 8:15 p.m. ET from NRG Stadium in Houston. The Texas have won five straight home games versus Buffalo. The latest Bills vs. Texans odds have Buffalo as the 5-point favorites. The over/under for total points scored is 44.5. Buffalo is at -265 on the money line (risk $265 to win $100), while Houston is at +215 (risk $100 to win $215).
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Written by Ross Kelly
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