The Cleveland Browns will continue to see who wins their quarterback competition when they take on the Buffalo Bills in Week 2 of the preseason on Saturday afternoon. Buffalo opened its preseason schedule with a 29-14 win over the Carolina Panthers, while Cleveland dropped a 34-10 decision to the Chicago Bears. Shedeur Sanders is expected to start at QB for the Browns, with Deshaun Watson and Dillon Gabriel both getting reps in the second half.
Kickoff is at 1 p.m. ET from Huntington Bank Field in Cleveland. The latest Bills vs. Browns odds have Cleveland as a 3-point favorite, while the over/under for total points scored is 36.5.
Before making any Bills vs. Browns picks, or 2026 NFL preseason Week 2 predictions of your own, you NEED to see what SportsLine expert Jeff Hochman has to say.
Hochman emerged on the sports betting scene in the 1990s. Today he's one of the nation's most respected and selective handicappers. He's 99-88-3 (+686) over the past five NFL seasons. Anybody following has seen STRONG returns!
Now, Hochman has locked in another confident pick for Bills vs. Browns.
He's leaning Under the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.
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