The Buffalo Bulls (4-7, 2-5 Mid-American) and Ball State Cardinals (5-6, 3-4) look to avoid ending their seasons with a losing streak when they meet in Muncie, Ind. for a MACtion showdown in the 2021 finale for both teams on Tuesday. Kickoff from Scheumann Stadium is set for 7 p.m. ET.

The Cardinals are 6.5-point favorites in the latest Ball State vs. Buffalo odds from Caesars Sportsbook, while the over-under for total points scored is 59.5. (See the latest college football lines for all of this week's games on our college football odds page.)

Before you consider your Buffalo vs. Ball State picks or college football predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

The model knows Ball State is coming off its second straight defeat, a 37-17 setback against Central Michigan in which it opened the scoring before falling behind by 18 points in the second quarter. The Cardinals allowed 567 yards of total offense and were outgained 285-159 on the ground. Freshman running back Carson Steele ran for a touchdown and fell seven yards shy of his third consecutive 100-yard performance and fourth in five games.

The model also knows Buffalo has lost three straight contests after dropping a 33-27 decision to Northern Illinois in overtime last week. Dylan McDuffie gained 125 yards on 29 carries for his fourth 100-yard effort in five games. The junior running back also ran for a touchdown, marking the sixth consecutive contest in which he rushed for a score.

Now the model has simulated Ball State vs. Buffalo 10,000 times, and the results are in. We can tell you that the model is leaning Under on the total, and it also says one side of the spread is hitting in well over 50 percent of simulations. You ABSOLUTELY need to see it before locking in your own picks.

Who wins Ball State vs. Buffalo? And which side of the spread hits in well over 50 percent of simulations? ... Join SportsLine right now to see which side of the Buffalo vs. Ball State spread you need to jump on Tuesday, all from the computer model on a 39-25 run on its top-rated college football side picks!