The 2025-26 College Football Playoff has three quarterfinal matchups on New Year's Day, with the 2026 Rose Bowl being the middle contest. It has the No. 1 Indiana Hoosiers taking on the No. 9 Alabama Crimson Tide. IU (13-0) is the lone undefeated squad in college football and last knocked off Ohio State, 13-10, in the Big Ten Championship Game. The Tide (11-3) defeated Oklahoma, 34-24, in the CFP First Round to advance to this stage.
Kickoff is at 4 p.m. ET from the Rose Bowl in Pasadena, Calif. The Hoosiers are 7.5-point favorites in the latest Indiana vs. Alabama odds, while the over/under is 47.5. IU is at -253 on the money line (risk $253 to win $100), while Bama is priced at +206 (risk $100 to win $206). Indiana is 8-5 against the spread this season, while Alabama is 8-4-2 ATS.
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Before making any Alabama vs. Indiana picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times, and it is 31-19 on its top-rated college football money-line picks since the beginning of the 2024 season.
The model has simulated Indiana vs. Alabama 10,000 times and the results are in. We can tell you that the model is going Over, and it also says one side of the spread hits well over 60% of the time!
So who wins Alabama vs. Indiana, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the Indiana vs. Alabama spread you need to jump on, all from the computer model that has simulated this game 10,000 times!
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Written by Ross Kelly
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