76ers vs. Celtics odds, line: Proven model reveals picks for NBA first round Game 2 matchup on Tuesday, April 21
The SportsLine Projection Model, up well over $10,000 on NBA picks over the past eight seasons, has locked in its bets for the Philadelphia 76ers vs. Boston Celtics Game 2 matchup
The Boston Celtics look to take a commanding 2-0 series lead when they take on the Philadelphia 76ers in Game 2 of their first round series on Sunday. Boston is coming off a 123-91 win in Game 1 on Saturday. The 76ers (45-37), the seventh seed in the East, are 22-20 on the road this season. The Celtics (56-26), the second seed, are 31-11 on their home court. Philadelphia is expected to be without Joel Embiid (appendectomy).
Tip-off from TD Garden in Boston is set for 7 p.m. ET. The Celtics lead the all-time playoff series 67-50. The Celtics are a 13.5-point favorite in the latest 76ers vs. Celtics odds, while the over/under for total points scored is 216.5.Â
Before making any 76ers vs. Celtics picks, you NEED to see what the SportsLine Projection Model has to say.
SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the 2026 NBA playoffs on a sizzling 23-9 roll (72%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!
The model has simulated 76ers vs. Celtics 10,000 times and the results are in. The model is going Under on the point total, and it also says one side of the spread hits well over 50% of the time!
Who wins 76ers vs. Celtics, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 23-9 roll on top-rated NBA picks!
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