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49ers vs. Buccaneers odds, line: 2024 NFL picks, Week 10 predictions from proven computer model

SportsLine's model has locked in its best bets for Sunday's game between the San Francisco 49ers and Tampa Bay Buccaneers

The San Francisco 49ers look to make a second half run after their bye week as they travel to the southeast to face off against the Tampa Bay Buccaneers on Sunday afternoon. San Francisco (4-4) beat Dallas, 30-24, in Week 8, while Tampa Bay (4-5) enters off an overtime loss at undefeated Kansas City, 30-24. The 49ers have won three straight games in this rivalry including a 27-14 home victory last November. San Francisco is 4-4 against the spread, while Tampa Bay is 5-4 ATS in 2024.

Kickoff from Raymond James Stadium is set for 1 p.m. ET. San Francisco is a 6.5-point favorite in the latest 49ers vs. Bucs odds via SportsLine consensus, while the over/under for total points is 50.5. The 49ers are -299 money line favorites (risk $299 to win $100), while the Bucs are +239 underdogs. 

Before making any Tampa Bay vs. San Francisco picks, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2024 NFL season on an incredible 14-7 hot streak on top-rated NFL picks this year. Longer term, it is on a 195-136 roll on top-rated NFL picks that dates back to the 2017 season and a 49-29 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following has seen HUGE returns!

The model has simulated 49ers vs. Bucs 10,000 times and the results are in. We can tell you the model is leaning Under on the total. It also says one side of the spread hits over 50% of the time!

Who wins Tampa Bay vs. San Francisco, and which side of the spread hits over 50% of the time? Join SportsLine right now to find out which side of the spread you should be all over, all from the model that is up well over $7,000 on its NFL picks!

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SportsLine Staff
SportsLine Staff

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