2026 MLB All-Star Game odds, predictions: AL vs. NL picks by expert on 118-66 roll

The National League looks for back-to-back wins in the MLB All-Star Game for the first time since 2011-12 when they take on the American League in the 2026 MLB All-Star Game on Tuesday in Philadelphia. The NL won in a 'swing off' last year after the game was tied through nine innings. Cristopher Sanchez will start in his home park for the NL, while Dylan Cease of the Toronto Blue Jays is on the hill for the AL. Shohei Ohtani (knee) and Aaron Judge (rib) are among the big names who will sit this game out. 

First pitch from Citizens Bank Park is set for 8 p.m. ET. The National League is a -142 favorite on the money line (risk $142 to win $100) in the latest 2026 MLB All-Star odds from FanDuel Sportsbook, with the AL at +120. The over/under is 7.5 runs. 

Before making any 2026 MLB All-Star Game picks or MLB predictions, you need to see what SportsLine's Matthew Severance has to say.

Severance is a well-connected writer and high-volume handicapper who has worked in the industry since 2005. After joining SportsLine, Severance quickly established himself as a top expert in multiple sports. Over the past four MLB seasons, he is up $1,681 and is SportsLine's No. 1 MLB expert. He also enters the break on a huge 118-66-1 roll on MLB picks, returning +1266! Anyone following could have seen HUGE returns.

Severance is going Under on the run total, and also has found a critical x-factor that makes one side the value pick! Additionally, he's locked in a must-see, plus-money parlay.

Who wins the 2026 MLB All-Star Game, and what critical X-factor makes one side a must-back? Join SportsLine right now to see which side of the 2026 MLB All-Star Game money line you need to jump on, all from the expert who enters the All-Star break on a huge 118-66-1 roll on MLB picks!

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