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2024 NFL Week 17 Lions vs. 49ers line, odds: Expert reveals pick for matchup on Monday Night Football

Micah Roberts, who is on a 27-6 roll on San Francisco 49ers games, has released his best bets for the Week 17 Detroit Lions vs. San Francisco 49ers MNF matchup

The Detroit Lions will try to become the first team since 2020 to go 8-0 on the road when they take on the San Francisco 49ers on Monday Night Football. The last team to accomplish that was the 2020 Kansas City Chiefs, who went 14-2 overall. The Lions (13-2), who have set a franchise record for wins, defeated the Chicago Bears, 34-17, in Week 16. The 49ers (6-9), who are fourth in the NFC West, dropped a 29-17 decision to the Miami Dolphins last week.

Kickoff from Levi's Stadium in Santa Clara, Calif., is set for 8:15 p.m. ET. Detroit is a 3.5-point favorite in the latest Lions vs. 49ers odds, while the over/under for total points scored is set at 50.5. The Lions are -203 money-line favorites (risk $203 to win $100), while the 49ers are +168 underdogs. Before making any Lions vs. 49ers bets or NFL predictions, you NEED to see which side SportsLine NFL expert Micah Roberts is on, considering his mastery of picks involving the 49ers.

Micah Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos' book director. Most importantly, Roberts has a strong read on the pulse of the 49ers. In fact, he is an AMAZING 27-6 (+2038) on his last 33 picks in games involving San Francisco! Anybody following is WAY UP!

Now, Roberts has locked in another confident against-the-spread pick for Lions vs. 49ers.

We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Lions vs. 49ers on Monday Night Football, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Lions vs. 49ers spread to back, all from the expert who is a blistering 27-6 on picks involving the 49ers!

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SportsLine Staff
SportsLine Staff

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