2024 NFL Week 15 Rams vs. 49ers line, odds: Expert reveals pick for matchup on Thursday Night Football

The Week 15 slate of games starts on Thursday Night Football with the Los Angeles Rams (7-6) visiting the San Francisco 49ers (6-7) . The Rams have won three of their last four games. Last Sunday, Los Angeles defeated the Buffalo Bills, 44-42. The 49ers are also coming off a win. In Week 14, San Francisco torched the Chicago Bears, 38-13. 

Kickoff at Levi's Stadium in Santa Clara, Calif., is set for 8:15 p.m. ET. San Francisco is a 2.5-point favorite in the latest Rams vs. 49ers odds, while the over/under for total points scored is 48.5. The 49ers are -147 money-line favorites (risk $147 to win $100), while the Rams are +124 underdogs. Before making any Rams vs. 49ers bets or NFL predictions, you NEED to see which side SportsLine NFL expert Micah Roberts is on, considering his mastery of picks involving the 49ers.

Micah Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos' book director. Most importantly, Roberts has a strong read on the pulse of the 49ers. In fact, he is an AMAZING 26-6 (+1938) on his last 32 picks in games involving San Francisco! Anybody following is WAY UP!

Now, Roberts has locked in another confident against-the-spread pick for Rams vs. 49ers.

We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Rams vs. 49ers on Thursday Night Football, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Rams vs. 49ers spread to back, all from the expert who is a blistering 26-6 on picks involving the 49ers!