Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you.
The Week 10 college football odds are filled with slim lines, which is appropriate given all of the intriguing ranked matchups. In just the SEC alone, there's Alabama vs. LSU (-5.5), Georgia vs. Ole Miss (+3.5) and Tennessee vs. Kentucky (+6.5) to make college football bets on. Elsewhere, we're blessed with a top-5 matchup as the No. 1 Miami Hurricanes visit No. 4 Notre Dame. The Irish are 4.5-point favorites as they look to avenge their defeat to Miami last season. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
Another top-10 matchup will take place between BYU and Utah in a series known as the Holy War. The Cougars have won each of the last three meetings, but the Utes are favored by 5.5 points in the Week 10 college football spreads. Outside of Miami and Utah, the only other undefeated squad in the UCLA Bruins are giving 6 points on the road at Minnesota.
Before making any college football picks for those games or others in Week 10, be sure to see what the SportsLine Projection Model has to say.
The model simulates every FBS game 10,000 times. It entered Week 10 with an 80-77 record on all top-rated college football picks this season.
Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 10 game, and the results are in.
One of the college picks the model is high on during Week 10: Ohio State (-7, 48.5) covers in over 60% of sims versus Oregon in a 3:30 p.m. ET kickoff. Another prediction: Oklahoma (+6.5, 45.5) covers versus Florida well over 50% of the time. The model also projects the Over to connect in 53% of simulations.
The model has also made the call on who wins and covers in every FBS matchup, including three upsets in ranked matchups per the poll rankings!
So which college football teams should you back in Week 10, and which three teams pull off upsets? ... Join SportsLine now to see who wins and covers every single game, all from the model that simulates every game 10,000 times!
Don't miss out: All new SportsLine memberships include Paramount+ Premium -- a $13.99/month value -- for no extra cost! Join now and get it all.
GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!
Written by Ross Kelly
View expert profile
