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Cardinals 2021 NFL schedule strength, win total, odds: Arizona all-in with additions of James Conner, AJ Green, Rodney Hudson, JJ Watt

Few teams were more active this offseason than the Arizona Cardinals, who have a 2021 Over/Under win total of 8 with a slew of new additions around Kyler Murray.
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The Arizona Cardinals haven't made the playoffs or finished with a winning record since losing in the NFC Championship Game following the 2015 season, but the Cards are clearly going all-in for the 2021 campaign around rising star quarterback Kyler Murray. After earlier adding former Pro Bowlers such as center Rodney Hudson, receiver AJ Green and three-time NFL Defensive Player of the Year JJ Watt, the team added another big name in running back James Conner. Arizona has an Over/Under win total of 8 this year, which seems a bit low.

The 2020 Cardinals finished 8-8 – they were 6-3 at one point and competing for the NFC West title but struggled down the stretch. A Week 17 loss at the Los Angeles Rams kept Arizona from the NFC's final wild-card spot.

Once the Cards were able to lure Watt to the desert, other players have followed. Green signed a one-year deal to pair with DeAndre Hopkins and essentially replace future Hall of Famer Larry Fitzgerald. An argument could be made that Hudson is the most important of the group as the three-time Pro Bowl could be the NFL's best center and is still just 31; Arizona got him in a trade with the Raiders. Hudson's 93.6 pass-blocking grade since 2015 is first among all centers.

The Pittsburgh Steelers opted not to bring back Conner, who essentially replaces Kenyan Drake (signed with Raiders) and will form a 1-2 punch in the backfield with Chase Edmonds – he is probably better suited to a pass-catching role as it is. Conner reunites with Cardinals running backs coach James Saxon, who was his position coach in Pittsburgh in 2017 and 2018.

Conner's best season was in 2018 when he was named to the Pro Bowl after rushing for 973 yards and 12 touchdowns, tied for the third most in the NFL that season, and catching 55 passes for 497 yards and a touchdown in 13 games. Staying healthy has always been Conner's problem.

Let's not also forget that Arizona upgraded at kicker with former Detroit Lion Matt Prater. He is the record-holder for the longest field goal in league history: 64 yards against Tennessee in 2013. Prater additionally holds league records for: most career field goals of 50 or more yards (59), consecutive made field goals of 50 or more yards (14) and consecutive field goal conversions of 55 or more yards (7).

Arizona's 2021 schedule ranks as tied for the 13th-toughest in the NFL as its 17 opponents – the added 17th was a trip to Cleveland – were a combined 138-134-0 last season.

Arizona Cardinals trends/William Hill Sportsbook odds

  • 2020 record: 8-8 (7-9 against the spread, 7-9 Over/Under)
  • 2021 strength of schedule rank: 13th-toughest (opponents' combined winning percentage of .507)
  • 2021 Over/Under win total: 8
  • SportsLine Projection Model forecasted wins: 9.2
  • Odds to win Super Bowl 56: +4000
  • To win NFC: +1600
  • To win NFC West: +550
  • To make playoffs: No -230, yes +190
  • NFL MVP odds: Kyler Murray +2000, DeAndre Hopkins +10000

Arizona Cardinals Home Opponents

  • Los Angeles Rams: Arizona is on a six-game SU and ATS home skid in series
  • San Francisco 49ers: Niners handed the Cards a crushing late-season home loss last year, 20-12
  • Seattle Seahawks: Cards snapped a seven-game home winless streak in series with wild 37-34 win last year
  • Green Bay Packers: Pack's first regular-season visit since 38-8 loss in 2015
  • Minnesota Vikings: Vikings have dropped their past two at the Cardinals, last in 2015
  • Houston Texans: Houston had made only two visits and lost them both, last in 2013
  • Indianapolis Colts: Cards are 2-1 SU & ATS at home in the series since Colts moved to Indy
  • Carolina Panthers: Carolina last visited in 2019 and won 38-20 as a short underdog

Arizona Cardinals Road Opponents

  • Los Angeles Rams: Arizona has dropped its past three at the Rams, going 0-2-1 ATS
  • San Francisco 49ers: Cards' only road loss in past six at Niners was 36-26 in 2019
  • Seattle Seahawks: Arizona's five-game ATS road win streak in series ended in 28-21 loss last year 
  • Chicago Bears: Chicago has lost (0-2 ATS) past two at home in series, last in 2015
  • Detroit Lions: Lions last hosted Cards in 2017 and Detroit won 35-23
  • Jacksonville Jaguars: Just three trips to Jacksonville for Arizona, which is 2-1 SU & ATS
  • Tennessee Titans: Cards have covered three straight games at Titans dating to Houston days
  • Dallas Cowboys: Teams played in Dallas last season and Cowboys were blown out 38-10
  • Cleveland Browns: Matchup of former Oklahoma QB Heisman winners in Kyler Murray vs. Baker Mayfield

Where does every player appear in our 2021 Fantasy football rankings? And which rookie quarterback will provide shocking value? Join SportsLine right now to get 2021 Fantasy football rankings, all from the model that simulated the entire season 10,000 times.

Matt Severance
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