The 2022 Week 10 NFL schedule closes out with a NFC East rivalry game between Taylor Heinicke and the Washington Commanders and Jalen Hurts and the Philadelphia Eagles on Monday Night Football. The undefeated Eagles are coming off a 29-17 win over the Houston Texans, while the Commanders are looking to bounce back from a 20-17 loss to the Minnesota Vikings. Before locking in any NFL DFS lineups for Monday Night Football on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who has been cashing big all season, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor has been spot-on all season, hitting on epic NFL DFS picks in primetime showdown matchups like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3), Amari Cooper (7-101-1), Nick Chubb (23-113-1), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4), Davante Adams (3-124-2), Justin Fields (179-1-1, 82-1), Diggs again in Week 8 (6-106-1), Chubb (23-101-2) and Cooper (5-131-1) again on MNF in Week 8, and Kelce again on Week 9 SNF (10-106). Anyone who has followed his picks is WAY UP!

Now, Kaylor has turned his attention to the Week 10 MNF matchup of Eagles vs. Commanders and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for Monday Night Football is Philadelphia wide receiver DeVonta Smith. "It may seem risky to target a guy who isn't even the No. 1 option on his own team, but I'll be doing just that with DeVonta Smith on Monday night. After back-to-back games with sub-standard DFS production, I believe Smith is primed to blow up for a huge night against the Commanders. In Philadelphia's first meeting with Washington in Week 3, the 2020 Heisman Trophy winner caught eight passes for 169 yards and a touchdown. Those numbers may be tough to duplicate, but I see something similar happening on Monday Night Football."

Kaylor is also targeting another under-the-radar player for MNF who could post HUGE numbers and carry your lineups to victory! His DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

Be sure to follow Jimmie (@jimmiekaylor) on Twitter for notifications about rosters changes/updates

What are the top NFL DFS picks for the MNF matchup of Eagles vs. Commanders on FanDuel and DraftKings? And which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, all from a DFS expert who already won a Millionaire Maker tournament in 2022!