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Kansas vs. Iowa State odds, line, spread: Proven model reveals college football picks, predictions for Week 5, 2022

The SportsLine projection model has a pick for the clash between Iowa State and Kansas. Here are the results:
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A Big 12 battle is on tap between the Kansas Jayhawks and the Iowa State Cyclones at 3:30 p.m. ET on Saturday at Kivisto Field at David Booth Kansas Memorial Stadium. Kansas has been one of the top storylines in college football so far this season, winning all four of its games. The Cyclones are favored by 3.5 points in the latest Kansas vs. Iowa State odds from Caesars Sportsbook, while the over/under is set at 58. 

Before you make any Iowa State vs. Kansas picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Kansas vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Kansas vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!

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SportsLine Staff

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