An American Athletic battle is on tap between the No. 24 Cincinnati Bearcats and the South Florida Bulls at 2:30 p.m. ET on Saturday at Nippert Stadium. Cincinnati is hoping to extend its four-game winning streak after beating Tulsa by 10 points last week. The Bearcats are favored by 27.5 points in the latest Cincinnati vs. South Florida odds from Caesars Sportsbook, while the over/under is set at 59.5.

Before you make any South Florida vs. Cincinnati picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Cincinnati vs. South Florida 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Cincinnati vs. South Florida? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!