The No. 2 Duke Blue Devils look for their second win in a row when they take on the Appalachian State Mountaineers in nonconference action on Thursday. Tip-off from Cameron Indoor Stadium in Durham, N.C., is set for 7 p.m. ET. Duke is favored by 21.5 points at Caesars Sportsbook, while the over-under for total points is set at 137.5 (see up-to-date odds for every game this week on our college basketball odds page).

Before making any Appalachian State vs. Duke picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Duke is led by freshman forward Paolo Banchero, who has been dominant since Day 1. Banchero is averaging 17.1 points, 7.2 rebounds, 2.3 assists and 1.6 steals per game, and is connecting on 49.5 percent of his shots from the floor as well as hitting 84.1 percent of his foul shots. He has scored in double figures in each game, including a 22-point performance in a season-opening 79-71 win over Kentucky on Nov. 9. He followed that up with his first double-double of his career, an 18-point and 12-rebound performance in an 82-56 win over Army on Nov. 12.

The model also knows guard Adrian Delph powers Appalachian State. The senior is averaging 15.8 points, 5.1 rebounds and one assist per game on 47.4 percent shooting from the floor, including 40.9 percent from beyond the arc. He is also a 79.2 percent free-throw shooter, among the best on the team. Delph has been solid on the road, averaging 16.3 points and 7.3 rebounds. He has reached double-figure scoring in nine games, including the first eight of the year. He poured in a season-high 39 points in a 75-68 loss to Delaware on Nov. 22.

Now, it has set its sights on Appalachian State vs. Duke. It is leaning Over on the total and it also says one side of the spread hits in well over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Appalachian State vs. Duke? And which side of the spread hits in well over 60 percent of simulations? ... Join SportsLine right now to find out which side of the Appalachian State vs. Duke spread you should be all over Thursday, all from the model on a roll on college basketball picks!