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2021 SportsLine Upset Bracket Full of Surprises

SportsLine simulated every possible matchup 10,000 times and the team that won over half the simulations was selected to advance. In order to "simulate the madness," we also assumed that the Nos. 3-6 seeds with the lowest win percentage when compared to other teams of the same seed would be upset. With this approach, we nailed 15 of the 26 double-digit seed upsets in the first round the past four tournaments!
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EAST REGION UPSETS: No. 12 Georgetown over No. 5 Colorado -- The Hoyas win almost 30 percent of simulations, the best of any No. 12 seed. No. 9 St. Bonaventure upends No. 8 LSU in the first round. No. 6 BYU over No. 3 Texas in the Sweet 16. BYU goes on to battle Michigan for a spot in the Final Four, but Michigan comes away with the win.

Get every pick, every play, every upset and fill out the rest of your bracket with our help! ... Join SportsLine here to see which No. 2 seed is a MUST-BACK, and see which region you need to pick the 10, 11, and 13 seeds, all from the model that's nailed 15 of the 26 double-digit seed upsets the past four tournaments!

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SportsLine Staff