The Monmouth Hawks will take on the Seton Hall Pirates at 8 p.m. ET Wednesday at Prudential Center. This is the season opener for both teams. Monmouth went 21-13 last season, while Seton Hall went 21-11.

The Pirates are favored by 21 points in the latest Seton Hall vs. Monmouth odds from Caesars Sportsbook, and the over/under is set at 135. Before you make any Monmouth vs. Seton Hall picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past six years, the proprietary computer model has generated an impressive profit of more than $1,200 for $100 players on its top-rated college basketball picks against the spread. Anybody who has followed it has seen profitable returns.

Now, it has simulated Seton Hall vs. Monmouth 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Monmouth vs. Seton Hall? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!