The fourth-ranked Ohio State Buckeyes look to secure their fourth straight Big Ten Conference Championship Game victory when they face the No. 14 Northwestern Wildcats on Saturday. Kickoff from Lucas Oil Stadium in Indianapolis is set for noon ET. The Buckeyes are 18.5-point favorites in the latest Northwestern vs. Ohio State odds from William Hill Sportsbook, while the over-under is 56 (For the latest college football predictions for all of this week's games, head over to our college football odds page).

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