With six-point teasers, the eyes are drawn immediately to underdogs of 1.5, 2 or 2.5. The additional half-dozen points for the 'dog take losses by three and seven -- the most frequent margins in NFL games -- out of play.

Week 4 affords us plenty of choices, with four matchups carrying such spreads.

For our two-team teaser, let's resist the temptation to grab a Great Dane-sized 'dog -- Houston +22 against Buffalo -- and settle on a pair of chihuahua-sized ones. Start by scratching the Colts (+2 at Miami), out of concern over Indianapolis QB Carson Wentz, hobbled by sore ankles. He never left the pocket last Sunday.

In a close call, eliminate the Vikings (+2 vs. Cleveland) because of uncertainty surrounding RB Dalvin Cook (ankle). Minnesota remains attractive even if Cook sits, but two other 'dogs earn a slight edge.

Read on to see our top teaser players on the spread, total and in primetime.

Which Week 4 spreads and totals represent the best teaser plays? And how should you tease the primetime matchups? ... Join SportsLine right now to see Week 4 teaser picks from the expert who returned more than $2,500 on his NFL picks from 2016-20 and hit 56 percent of his ATS picks last year!