The byes are over. We don't have that many weekends with a full inventory of games left to wager. The holidays giveth and taketh away.

Weather played games with us a bit last week, with some of the early forecasts looking downright brutal, only for almost all of those games to end up being not impacted at all by the wind or other conditions. We aren't going to fall for that again this time. But we do see ample potential to jump on some totals early in the week, because we strongly suspect these numbers will be changing as more money comes in.

Before you make any Week 15 picks, you'll want to see what NFL insider Jason La Canfora has to say. La Canfora has taken an early look at the games and found a number of best bets and lines to keep an eye on. One of the matchups he's monitoring? Chargers at Radiders, which offers value right now. You NEED to see his analysis before locking in any NFL picks of your own.

Jason also has a slate of best bets for tonight's Monday Night Football action, which we'll share below.

• More Week 15 picks: Model | Parlay

Which lines are worth jumping on right now, and what are the best plays for Monday Night Football? Join SportsLine right now to see all Jason La Canfora's NFL Week 15 betting primer!