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MLB playoffs Astros vs. White Sox odds, lines: Proven model reveals picks for ALDS Game 4 showdown

SportsLine's Projection Model has generated picks for Tuesday's ALDS Game 4 matchup between the Houston Astros and Chicago White Sox
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The Houston Astros will get a second chance to close out the Chicago White Sox when they meet in Game 4 of the American League Division Series on Tuesday afternoon at Guaranteed Rate Field in Chicago. Game 4 was initially scheduled for Monday but had to be postponed due to inclement weather. The White Sox rallied from a four-run deficit to post a 12-6 triumph in Game 3.

Chicago is the -111 favorite (risk $111 to win $100) in the latest Astros vs. White Sox odds from Caesars Sportsbook while Houston is a +101 underdog. The Over/Under for total runs scored is 8.5. First pitch is at 2:07 p.m. ET on Tuesday. (See the latest lines for every game on our MLB odds page.)

Before making any Astros vs. White Sox picks, check out the latest MLB playoff predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, enters the second week of the 2021 MLB playoffs with a 207-175 record on top-rated MLB money-line picks, returning well over $700. It also had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. Anyone following it has seen some HUGE returns!

Now, the model has set its sights on Astros vs. White Sox. We can tell you it's leaning Over the total, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Game 4 of the ALDS and Astros vs. White Sox? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the Astros vs. White Sox money line you should be all over on Monday, all from the model that is crushing its MLB picks in 2021!

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SportsLine Staff