The teams with best records in baseball conclude their three-game series on Wednesday afternoon when the Chicago White Sox host the Tampa Bay Rays at Guaranteed Rate Field in Chicago. First pitch is 2:10 p.m. ET. The White Sox are -135 money-line favorites in the latest Rays vs. White Sox odds from William Hill Sportsbook, while the Rays are +125 underdogs. 

The game is one of 15 on Wednesday's loaded MLB schedule. (See up-to-date lines for every game on our MLB odds page.)

Before entering any MLB picks or parlays, you NEED to see the latest predictions from the SportsLine Projection Model. 

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It's off to a sizzling start in 2021, going 89-65 on top-rated MLB money-line picks through 11 weeks, returning well over $1,200. Anyone following it has seen huge rewards.

Now, the model has set its sights on the MLB schedule for Wednesday. Using its top picks for the day, the model has generated a four-leg parlay that would pay more than 8-1! The best part is that the parlay doesn't start until 7:20 p.m. ET, giving you plenty of time to make your MLB picks!

We can tell you that one of the picks is the Dodgers (-145) to beat the Phillies at 10:10 p.m. ET. But the model has three other picks, including an American League underdog winning 65 percent of the time! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So which American League underdog is a MUST-BACK? And what other teams do you need to include in your parlay for an 8-1 payout? ... Join SportsLine right now to find out which picks you should be all over on Wednesday, all from the model that is off to a fast start in 2021!