The Los Angeles Dodgers and San Diego Padres play the second game of their key three-game series on Wednesday when the two teams collide at Petco Park in San Diego. First pitch is 10:10 p.m. ET. The Dodgers are -140 money-line favorites in the latest Dodgers vs. Padres odds from Caesars Sportsbook, while the Padres are +130 underdogs. 

The game is one of 14 on Wednesday's loaded MLB schedule. (See up-to-date lines for every game on our MLB odds page.)

Before entering any MLB picks or parlays, you NEED to see the latest predictions from the SportsLine Projection Model. 

This model, which simulates every pitch of every game 10,000 times, is 166-137 on top-rated MLB money-line picks through 21 weeks in the 2021 season, returning well over $400. It also had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. Anyone following it has seen some huge returns.

Now, the model has set its sights on the MLB schedule for Wednesday. Using its top picks for the day, the model has generated a four-leg parlay that would pay more than 12-1! The best part is that the parlay doesn't start until 6:30 p.m. ET, giving you plenty of time to make your MLB picks!

We can tell you that one of the picks is the Nationals (-111) to beat the Marlins (7:10 p.m. ET). But the model has three other picks, including a National League underdog pulling off a big upset! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So which underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of 12-1? ... Join SportsLine right now to find out which picks you should be all over on Wednesday, all from the model that is off to a fast start in 2021!