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Kentucky vs. Missouri odds, line, spread: Proven model reveals college football picks, predictions for Week 2, 2021

The SportsLine projection model has a pick for the clash between Missouri and Kentucky.
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An SEC battle is on tap between the Kentucky Wildcats and the Missouri Tigers at 7:30 p.m. ET on Saturday at Kroger Field.

Both teams started the season with a win. Kentucky blew out Louisiana-Monroe at home, 45-10 and Missouri held off Central Michigan, 34-24. The Wildcats are favored by 5.5. points in the latest Kentucky vs. Missouri odds from Caesars Sportsbook, and the over-under is set at 57. Before you make any Missouri vs. Kentucky picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It also enters Week 1 of the 2021 season on a 57-37 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Kentucky vs. Missouri 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits more than 50 percent of the time. You absolutely need to see it before locking in your own picks.

So who wins Kentucky vs. Missouri? And which side of the spread hits more than 50 percent of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks. .. If you're already a member, see the picks below!

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SportsLine Staff