The No. 17 Iowa Hawkeyes will look to rebound against the No. 10 Penn State Nittany Lions when they meet in a Big Ten Conference crossover college football matchup on Saturday at 7:30 p.m. ET from Kinnick Stadium in Iowa City, Iowa. The Hawkeyes are coming off their first loss of the season last week at Michigan. Penn State is a 3.5-point favorite in the latest Penn State vs. Iowa odds, while the over-under for total points scored is 43. Before making any Penn State vs. Iowa picks of your own, be sure to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen huge returns. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,300 for $100 players on its top-rated college football against-the-spread picks.  

The model enters Week 7 of the 2019 season on a strong run, going 68-42 on its top-rated college football picks. It also called Georgia (-27.5) covering against Tennessee and California (+21) easily staying well within the spread against Oregon last week. Anybody who has been following it is WAY UP.

Now, it has set its sights on Penn State vs. Iowa. We can tell you it's leaning under, and it's also generated an against the spread pick that cashes in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

Who wins Penn State vs. Iowa? And which side of the spread is hitting well over 50 percent of the time? ... Join SportsLine right now to see which side of the Penn State vs. Iowa spread to back on Saturday, all from the advanced model on a 68-42 run on top-rated picks!