The  No. 23 BYU Cougars and the Santa Clara Broncos are set to square off in a West Coast matchup at 9 p.m. ET Thursday at Marriott Center. The Cougars are 21-7 overall and 12-1 at home, while Santa Clara is 18-9 overall and 3-5 on the road. BYU is second in the West Coast; Santa Clara is seventh. The Cougars are favored by 14.5 points in the latest Brigham Young vs. Santa Clara odds, while the Over-Under is set at 150. Before you make any Santa Clara vs. Brigham Young picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

This model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. It also entered Week 16 of the 2019-20 season on a 54-30 run on all top-rated college basketball picks. Anybody who followed it has seen huge returns.

Now, it has simulated Brigham Young vs. Santa Clara 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Brigham Young vs. Santa Clara? And which side of the spread is hitting in well over 50 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!