The New York Giants will take on the San Francisco 49ers at 1 p.m. ET on Sunday at MetLife Stadium. The Giants are 0-2 and San Francisco is 1-1. San Francisco is favored by 3.5 points in the latest Giants vs. 49ers odds from William Hill, and the Over-Under is set at 41.5. Before you make any 49ers vs. Giants picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up over $7,300 for $100 players on its top-rated NFL picks since its inception five-plus years ago. It's off to a strong 5-2 roll on top-rated NFL picks this season. The model enters Week 3 on an incredible 101-67 roll on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, it has simulated Giants vs. 49ers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

So who wins Giants vs. 49ers? And which side of the spread has all the value? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks... If you're already a member, see the picks below!