Pittsburgh vs. Jacksonville odds, line, spread: Proven model reveals college basketball picks, predictions for Dec. 21, 2021

The Pittsburgh Panthers will take on the Jacksonville Dolphins at 2 p.m. ET on Tuesday at Petersen Events Center. The Panthers are 4-7 overall and 3-5 at home, while Jacksonville is 7-3 overall and 2-3 on the road. Pittsburgh is coming off a 59-57 win over St. John's in New York on Saturday.  

The Panthers are favored by 4.5 points in the latest Pittsburgh vs. Jacksonville odds from Caesars Sportsbook, while the over-under is set at 118. Before you make any Jacksonville vs. Pittsburgh picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Pittsburgh vs. Jacksonville 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Pittsburgh vs. Jacksonville? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.