Michigan State vs. Minnesota odds, line, spread: Proven model reveals college football picks, predictions for Week 4, 2022

A Big Ten battle is on tap between the Michigan State Spartans and the Minnesota Golden Gophers at 3:30 p.m. ET on Saturday at Spartan Stadium. Minnesota is looking to remain unbeaten following its 49-7 win over Colorado last week. The Golden Gophers are favored by 2.5 points in the latest Michigan State vs. Minnesota odds from Caesars Sportsbook, while the over/under is set at 51. 

Before you make any Minnesota vs. Michigan State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Michigan State vs. Minnesota 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Michigan State vs. Minnesota? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!