Kentucky vs. Louisville odds, lines: Advanced computer college basketball model releases picks

The Louisville Cardinals will look to snap a three-game losing streak to the Kentucky Wildcats when they meet in a key non-conference matchup on Saturday. Tip-off from KFC Yum! Center in Louisville, Ky., is set for 1 p.m. ET. Louisville is favored by 4.5-points, while the Over-Under is set at 133.5 (see up-to-date predictions for every game this week on our college basketball odds page). 

Before making any Kentucky vs. Louisville picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,600 for $100 players on its top-rated college basketball picks against the spread. It's off to a profitable start in the 2020-21 season, going 12-9 on all its top-rated picks and returning almost $300. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Kentucky vs. Louisville. We can tell you the model is leaning over the total, and it also says one side of the spread hits in 70 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Kentucky vs. Louisville? And which side of the spread hits in 70 percent of simulations? ... Join SportsLine right now to find out which side of the Kentucky vs. Louisville spread you should be all over Saturday, all from the model on a roll on college basketball picks!