East Carolina vs. Tulane odds, line: 2025 college football picks for Week 7 predictions from proven model

The East Carolina Pirates (3-2) and the Tulane Green Wave (4-1) match up in an American Conference tilt on Thursday evening. On Sept. 25, the Pirates defeated Army 28-6. As for Tulane, they took down Tulsa 31-14 last week. East Carolina leads the all-time series 12-8 over Tulane. 

Kickoff from Benson Field at Yulman Stadium in New Orleans, La., is at 7:30 p.m. ET. The Green Wave are 6.5-point favorites in the latest East Carolina vs. Tulane odds, while the over/under for total points scored is 53.5 via SportsLine consensus. The Under is a combined 7-3 for the teams this season. Tulane is at -231 on the money line (risk $231 to win $100), while ECU is at +190 (risk $100 to win $190).

Before making any East Carolina vs. Tulane picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 38-25 combined on money-line and over/under picks since the beginning of 2024. Anyone following could have seen impressive returns.

The model has simulated East Carolina vs. Tulane 10,000 times and the results are in. We can tell you that the model is leaning under, and it also says one side of the spread has all the value!

So who wins East Carolina vs. Tulane, and which side of the spread has all the value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!