Colorado vs. Minnesota odds, line, spread: Proven model reveals college football picks, predictions for Week 3, 2021

The Colorado Buffaloes will take on the Minnesota Golden Gophers at 1 p.m. ET on Saturday at Folsom Field. Both teams sport 1-1 records as Colorado won its opener before losing last week, while Minnesota won last week but lost its opener. Colorado ended last year second in the Pac-12's South Division, while the Golden Gophers ended up fourth in the West Division of the Big Ten. 

The Buffaloes are favored by two points in the latest Colorado vs. Minnesota odds from Caesars Sportsbook, and the over-under is set at 50. Before you make any Minnesota vs. Colorado picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Colorado vs. Minnesota 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Minnesota vs. Colorado? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!