Grizzlies vs. Timberwolves prediction, odds, line: Proven model reveals 2025 NBA picks for Dec. 17

A pair of surging Western Conference teams will meet on Wednesday's NBA schedule as the Minnesota Timberwolves host the Memphis Grizzlies. Both teams are 7-3 over their last 10 games, with Minnesota 17-9 on the season, while Memphis is 12-14. This is the first meeting of the season between the two. Ja Morant (ankle) is doubtful for Memphis, while Anthony Edwards (foot) is questionable for Minnesota.

Tipoff is at 8 p.m. ET from the Target Center in Minneapolis. The latest Grizzlies vs. Timberwolves odds have Minnesota as the 8.5-point favorite, while the over/under is 229.5.

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Before making any Timberwolves vs. Grizzlies picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 9 of the 2025-26 NBA season on a sizzling 29-14 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Grizzlies vs. Timberwolves 10,000 times and the results are in. We can tell you that the model is going Under on the point total, and it also says one side of the spread hits in well over 50% of simulations!

Who wins Timberwolves vs. Grizzlies, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the Grizzlies vs. Timberwolves spread you should be all over, all from the model on a 29-14 roll on top-rated NBA spread picks!

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