Chiefs vs. Chargers odds, Thursday Night Football spread: Proven model reveals NFL picks, predictions for TNF

The Kansas City Chiefs (9-4) and the Los Angeles Chargers (8-4) will meet on Thursday Night Football in Week 15. The Chiefs have won six straight games and are in first place in the AFC West. Kansas City completely dominated the Las Vegas Raiders in Week 14, blowing them out 48-9. Los Angeles is on a two-game win streak and cruised to a 37-21 victory at home against the New York Giants last week.

Kickoff from SoFi Stadium is set for 8:20 p.m. ET. Kansas City is favored by three points in the latest Chiefs vs. Chargers odds from Caesars Sportsbook, while the Over-Under is 54. Before making you make any Chiefs vs. Chargers picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model knows Chiefs quarterback Patrick Mahomes is fourth in the NFL in passing yards (3,642), fifth in passing touchdowns (27), and ninth in QBR (57.3). The Texas Tech product has tossed at least two passing touchdowns in eight games this season. In the blowout win against the Las Vegas Raiders, he went 20-of-24 for 258 yards and two passing touchdowns. 

The model also knows Chargers quarterback Justin Herbert is having an outstanding year. Herbert is third in the NFL in passing yards (3,822), second in passing touchdowns (30), and second in QBR (67.5). The 2020 sixth overall pick cooked the Giants' defense last week, going 23-of-31 for 275 yards with three passing touchdowns. This was the sixth game of the year in which Herbert tossed at least three touchdowns. 

Now, the model has set its sights on Chiefs vs. Chargers on Thursday Night Football. We can tell you it's leaning Under the point total, and it also says one side of the spread cashes in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any Chiefs vs. Chargers picks of your own.

So who wins Chiefs vs. Chargers on Thursday Night Football? And which side of the spread cashes well over 50 percent of the time? ... Join SportsLine right now to see which side of the Chiefs vs. Chargers spread to back, all from the dialed-in NFL model that's up almost $7,000 on top-rated NFL picks!