2021 NCAA Tournament Optimal Bracket Simulation: Model on epic run reveals picks, predictions

In this bracket, the team that wins more than 50 percent of computer simulations is picked to advance each round. Our optimal bracket beat almost 90% of CBS Sports Bracket Challenge players over the past two years.

SportsLine Staff

No. 1 seed Baylor is a strong pick to come out of this region despite losses to Kansas and Oklahoma State. The Bears are our second-best team in neutral-site power ranking, better than fellow 1-seeds Michigan and Illinois. And they have the second-best chance of winning the tournament of any team at 20.7 percent.

Get every pick, every play, every upset and fill out the rest of your bracket with our help! ... Join SportsLine now to see which No. 2 seed is a must-back, and which region features multiple double-digit seeds delivering huge upsets in the first round, all from the model that nailed 15 of the 26 double-digit upsets the last four tournaments!