The Broncos could not have looked worse in Week 1. ...

Drew Lock will start for the defending champs. ...

The Saints have covered six straight road games. …

The Jets get a much tougher test in Week 2. ...

DJ Moore might not be a prototypical No. 1 receiver, but he is unquestionably the Bills' top wideout. And this Lions' defense just gave up 182 receiving yards to Chris Olave. The Lions remain without safeties Brian Branch and Kerby Joseph, and on Tuesday they added corner D.J. Reed to the injury report, listing him as limited with a foot injury. Even if he suits up, I love Moore to notch 60-plus receiving yards in what should be a shootout.

Kenneth Walker's backups are fifth-round rookie Emmett Johnson and pass-catcher Brashard Smith. The Chiefs are starting undrafted rookie Khalil Benson at left tackle. He's a better run-blocker than pass-blocker, and he'll struggle against Denver's Nik Bonitto (27.5 sacks last two seasons). With Patrick Mahomes returning from a torn ACL and LCL, look for the Chiefs to lean on their big free-agent acquisition. Even if Walker is inefficient early, Andy Reid will stick with him because Walker always is a threat to bust a long run.

Bo Nix says he won't hesitate to run this season, despite the fact he's coming back from a fractured right ankle. In Kansas City last season, he rushed nine times for 42 yards. In each of his two previous NFL season openers, Nix shown a willingness to run. Look for Nix to scramble enough to clear this discounted number.

I trust Kevin O’Connell to design an offense around Kyler Murray’s strengths. While Murray’s acquisition dominated offseason coverage, Minnesota made a defensive move that could prove almost as important, signing James Pierre. The former Steeler graded out last season as the NFL’s top cover corner, per PFF. The Packers could get off to a slow start until their offensive line comes together and Micah Parsons returns.

Joe Burrow has played in six season openers, and the Bengals are 1-5 ATS. Even the preseason snaps he got last year did not lead to a strong offensive performance, as Cincy survived 17-16 in Cleveland. The Bucs have won four straight season openers. Their top two draft picks -- edge Rueben Bain Jr. and linebacker Josiah Trotter -- should make an immediate impact on a unit that was able to retain Vita Vea as the defensive anchor. With Baker Mayfield out to prove himself worthy of the big contract extension he just received, I took the points.

Colts coach Shane Steichen faced off with Jesse Minter last season, when Minter served as the Chargers' defensive coordinator. The Colts shredded LA 38-24, with Jonathan Taylor and Daniel Jones accounting for five touchdowns. I'm not expecting that kind of offfensive outburst Sunday in Indianapolis, when Minter's Ravens visit. But Baltimore shouldn't be laying over a field goal. The Colts start the season with DeForest Buckner, Sauce Gardner and Charvarius Ward healthy. Somehow, Daniel Jones looks recovered from his torn Achilles tendon. And Alec Pierce is expected to play through his heel injury. Grab the points.

The Ravens were vulnerable to slot receivers last season, and Sunday's matchup sets up well for Josh Downs. Michael Pittman Jr. is gone. Keenan Allen is available but aging and relatively new to the offense. And Alec Pierce has been limited with a heel injury. Look for Downs to clear this relatively modest number in a high-scoring environment.

The Jets will get improved QB play after struggling with the trio of Justin Fields, Tyrod Taylor and Brady Cook last season. In his only preseason appearance, Geno Smith completed 7 of 7 throws for 65 yards and a touchdown. Titans fans had to be alarmed after watching their first stringers get dominated by Seattle's backups. Tennessee's starters played three possessions and trailed 16-3 after the first quarter. In fact, Cam Ward did not complete a pass longer than seven yards in 24 preseason attempts over two appearances. Aaron Glenn's new-look defense, featuring Minkah Fitzpatrick, Demario Davis, T'Vondre Sweat, David Onyemata and No. 2 overall pick David Bailey, should be the best unit on the field Sunday.

In his last eight regular-season games, Brock Purdy cleared this prop total twice, each time by a half-yard. He's facing a fierce Rams' pass rush led by Myles Garrett (23 sacks), Byron Young (12 sacks) and Kobie Turner (7 sacks). The Rams also upgraded their secondary with the additions of corners Trent McDuffie and Jaylen Watson. I'm expecting a lot of short, quick throws from Purdy and bet against him completing one of 38-plus yards.

Deebo Samuel is back in a comfortable offensive system, and the 49ers need him. George Kittle returns from a serious injury and could be limited. Mike Evans dealt with multiple injury issues during training camp, and the other primary target (outside of Christian McCaffrey) is rookie De'Zhaun Stribling. Look for Samuel to be heavily involved vs. the Rams.

DeMario Douglas caught five of seven targets for 45 yards in the Super Bowl loss to the Seahawks. Stefon Diggs is gone, so Douglas should be the primary slot receiver. That's an important role against a Seahawks defense that could be missing Nick Emmanwori (ankle). With Seattle focused on slowing down A.J. Brown and Romeo Doubs on the outside, look for Douglas to notch at least 20 receiving yards.