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    Seahawks vs. 49ers NFL Week 2 injury report, odds: Jamal Adams done for season, Elijah Mitchell out, George Kittle may sit

    Both Seattle and San Francisco will be missing at least one key player on Sunday.
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    It's a short week for the Seattle Seahawks after their upset of Denver on Monday night as they visit San Francisco on Sunday in the 49ers' home opener, and both clubs will be missing at minimum one key player: Seattle Pro Bowl safety Jamal Adams is done for the season and 49ers top running back Elijah Mitchell will miss about eight weeks. Niners Pro Bowl tight end George Kittle also is likely to sit but nothing official yet. San Francisco was a double-digit favorite at Caesars Sportsbook earlier this week but is down to -8.5.

    On Wednesday, Seahawks coach Pete Carroll said Adams was still deciding on the best options to repair an injury to his quadriceps tendon suffered in the season opener, but NFL Network's Ian Rapoport is reporting that Adams will indeed have season-ending surgery. He had three tackles and a pass defensed against the Broncos. The three-time Pro Bowler – who was the league's highest-paid safety for a while -- hasn't played more than 12 games with Seattle due to injury since being traded from the Jets, and that trend obviously will continue.

    In the 25 games he has played, the Seahawks are 14-11. Adams set the NFL's all-time sack record for a defensive back with 9.5 in 2020. But Pro Football Focus ranked him 53rd among 94 safeties in the league for the season. Last year, when Adams had zero sacks, PFF ranked him 63rd of 91 before his labrum tear and 85th in pass defense. After Adams exited Monday's win early in the second quarter, veteran Josh Jones took his place alongside starting free safety Quandre Diggs. Playing 53 snaps, Jones produced seven tackles.

    Mitchell sprained the MCL in his right knee in the Niners' upset Week 1 loss in Chicago and will miss about two months. He had six carries for 41 yards before the injury. Last year as a sixth-round rookie, Mitchell rushed for 963 yards and five scores. San Francisco has yet to have a 1,000-yard rusher in Kyle Shanahan's tenure, in part due to injuries, but also because he likes a tailback-by-committee approach. Shanahan said "we'll go with the hot hand in the game" with Mitchell sidelined.

    Jeff Wilson was probably the No. 1 Fantasy football pickup this week but rookies Tyrion Davis-Price and Jordan Mason also should see snaps. The club also signed former Indianapolis Colts running back Marlon Mack to its practice squad.

    It's not looking good for Kittle on Sunday after he missed the opener with a groin injury and hasn't practiced yet this week. The two tight ends used in his place vs. Chicago, Ross Dwelley and Tyler Kroft, each had one just catch for a combined 20 yards as Trey Lance struggled in the rain. The calls for Jimmy Garoppolo will be deafening if Lance struggles again in agreeable conditions and the Niners are upset. 

    Looking for the best picks against the spread, sharp plays on the total and props you can take straight to the pay window? Join Jonathan Coachman on The Early Edge as he speaks with SportsLine's top handicappers to preview the day's biggest games. We promise to keep it short and sweet and to put some green in your pocket. The Early Edge is in your feed every single day by 11 a.m. ET. Subscribe right here on YouTube to watch daily, plus don't miss The Early Edge specials and live shows!

    Matt SeveranceSeverance Pays

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