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Cowboys vs. Eagles spread, odds, picks: Andy Dalton, Miles Sanders expected out, but Jalen Reagor will play

There's a long list of injury news surrounding Sunday night's Cowboys at Eagles matchup.
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The Dallas Cowboys are the first team in the NFL to start 0-7 against the spread since the 2006 Miami Dolphins and look to avoid becoming the first club since the 2003 Oakland Raiders to begin 0-8 ATS. However, Dallas is expected to be without starting quarterback Andy Dalton on Sunday night in Philadelphia, which is a 10-point favorite on the William Hill NFL odds. The Eagles likely will be down top running back Miles Sanders but will get back exciting rookie wideout Jalen Reagor.

The Cowboys are 0-2 in Dalton's two starts. He was not good on Oct. 19 in a 38-10 home loss to Arizona and then was 9-for-19 for 75 yards with a pick last week in a 25-3 loss at Washington before being knocked out with a concussion on a dirty hit.

Thus, barring something very unforeseen seventh-round rookie Ben DiNucci will make his first start – the first rookie to start at QB for Dallas since now-injured Dak Prescott (fourth-round pick) in Week 1 of the 2016 season. Prescott was 25-for-45 for 227 yards in a 20-19 loss to the Giants but would go on to win NFL Offensive Rookie of the Year.

DiNucci at least should bring a running threat that Dalton didn't. The last 11 quarterbacks to make their first career start in primetime are 10-1 ATS and SU. However, this spread has rocketed up from Eagles -3.5 with the likelihood that it's DiNucci under center.

As for the Eagles, Sanders is expected to miss his second game in a row with a knee injury – he leads all NFL running backs in yards per carry at 6.1. Very good player but perhaps proving a bit brittle as this will be Sanders' third game missed of 2020 (also Week 1). Boston Scott rushed for 46 yards on 12 carries and had three catches for 46 yards and a TD starting for Sanders in last Thursday's 22-21 comeback win over the Giants.

Philadelphia badly needs receiver reinforcements with DeSean Jackson hurt yet again and perhaps out for the season and Alshon Jeffery still yet to play off foot surgery.

Reagor, the No. 21 overall pick in April's draft, will play for the first time since Week 2. He came off injured reserve early this week a bit earlier than expected as his thumb surgery originally had a 6-8-week timetable. The burner out of TCU had one catch for 55 yards in his NFL debut and then four catches for 41 yards in Week 2 before the injury.

It's also possible that No. 2 tight end Dallas Goedert could play – which would be a huge boost with No. 1 Zach Ertz out at least a few more weeks due to injury. Goedert had caught 13 passes for 138 yards and a touchdown this season before suffering a high ankle sprain and a cracked tibia in Week 3 vs. Cincinnati.

At 2-4-1, the Eagles lead Washington (2-5) and Dallas (2-5) by a half-game atop the NFC East. William Hill lists Philly as the -165 favorite with the Cowboys at +350 and Football Team (off this week) at +425.

So far, the SportsLine experts are on the Eagles for Sunday's game. 

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SportsLine Staff