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Bills vs. Lions prediction, props, odds: Top NFL expert reveals Thanksgiving Day player prop bet picks for Week 12 game

Alex Selesnick studied the Detroit Lions vs. Buffalo Bills Thanksgiving Day game and revealed his Week 12 NFL player props
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Josh Allen and the Buffalo Bills (7-3) hit the road to take on the Detroit Lions (4-6) in a Thanksgiving Day matchup that projects to be a high-scoring affair. Kickoff is at 12:30 p.m. ET. Buffalo is favored by 9.5 points in the latest Lions vs. Bills odds from Caesars Sportsbook, and the over/under is set at 54.5 points. In addition to the Bills vs Lions point spread and Week 12 NFL betting lines, Caesars is also offering a plethora of prop bet options for this matchup on Thanksgiving Day, and SportsLine NFL expert Alex Selesnick has just revealed his top plays.

Selesnick (aka PropStarz) specializes in NFL, MLB and NBA prop betting, where he implements a combination of research, statistical analysis and mathematical modeling. 

After nailing three of his four NFL props on Sunday, the expert is an impressive 24-11 on NFL prop picks for SportsLine through the first nine weeks, after going an impressive 53-37 during the 2021 regular season. He is 58-34 (+15.80 units) overall on his SportsLine NFL prop picks. He also went 130-89 (+26.69 units) on MLB prop plays during the 2022 regular season and is up nearly 235 units on NBA props and futures plays over the past two-plus seasons.

Now, PropStarz has locked in on Bills vs. Lions and just revealed his top prop bet picks for this Week 12 Thanksgiving Day NFL matchup. We can tell you that one prop bet Selesnick is backing is Bills All-Pro wide receiver Stefon Diggs to go over 88.5 receiving yards.

Stefan Diggs Over 88.5 Receiving Yards -114

"Diggs is quietly having a career season while averaging while avearging over 100 receiving yards per game. Now he gets to play indoors, on a fast track, against the worst passing defense in the NFL. You couldn't ask for better conditions for a potential spike game for the stud WR. I expect the Bills passing offense to have a dominant performance in a game with sneaky shootout potential." 

What other prop bets is PropStarz targeting for the Lions vs. Bills Thanksgiving Day matchup? And what Josh Allen prop is a must-back? ... Join SportsLine now to see PropStarz's Thanksgiving Day NFL props for Bills vs. Lions, all from the expert who has consistently crushed his NFL prop bet picks for SportsLine! 

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SportsLine Staff

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